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Nucleolar caspase-2: Protecting us from DNA damage

Caspase-2 triggers apoptosis, but how it is activated by different stimuli is unclear. In this issue, Ando et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608095) delineate two pathways of caspase-2 activation and show that, in response to DNA damage, caspase-2 forms a complex with the PI...

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Detalles Bibliográficos
Autores principales:	O’Byrne, Kenneth J., Richard, Derek J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461038/ https://www.ncbi.nlm.nih.gov/pubmed/28500181 http://dx.doi.org/10.1083/jcb.201704114

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