Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro

Interferon regulatory factor 8 (Irf8) is a transcription factor that negatively regulates osteoclast differentiation and Irf8 global knockout (Irf8 (−/−)) mice have been shown to have reduced bone volume resulting from increased osteoclast numbers. However, detailed analysis of the functions of Irf8...

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Detalles Bibliográficos
Autores principales: Saito, Emi, Suzuki, Dai, Kurotaki, Daisuke, Mochizuki, Ayako, Manome, Yoko, Suzawa, Tetsuo, Toyoshima, Yoichi, Ichikawa, Takahiro, Funatsu, Takahiro, Inoue, Tomio, Takami, Masamichi, Tamura, Tomohiko, Inagaki, Katsunori, Kamijo, Ryutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461233/
https://www.ncbi.nlm.nih.gov/pubmed/27502007
http://dx.doi.org/10.1007/s10616-016-0013-z

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