Induced Regulatory T Cells Superimpose Their Suppressive Capacity with Effector T Cells in Lymph Nodes via Antigen-Specific S1p1-Dependent Egress Blockage

Regulatory T cells (Tregs) restrict overexuberant lymphocyte activation. While close proximity between Tregs and their suppression targets is important for optimal inhibition, and literature indicates that draining lymph nodes (LNs) may serve as a prime location for the suppression, signaling detail...

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Detalles Bibliográficos
Autores principales: Geng, Shuang, Zhong, Yiwei, Zhou, Xiaoyu, Zhao, Gan, Xie, Xiaoping, Pei, Yechun, Liu, Hu, Zhang, Huiyuan, Shi, Yan, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461288/
https://www.ncbi.nlm.nih.gov/pubmed/28638384
http://dx.doi.org/10.3389/fimmu.2017.00663

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