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Anti-Bovine Programmed Death-1 Rat–Bovine Chimeric Antibody for Immunotherapy of Bovine Leukemia Virus Infection in Cattle

Blockade of immunoinhibitory molecules, such as programmed death-1 (PD-1)/PD-ligand 1 (PD-L1), is a promising strategy for reinvigorating exhausted T cells and preventing disease progression in a variety of chronic infections. Application of this therapeutic strategy to cattle requires bovinized chi...

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Detalles Bibliográficos
Autores principales:	Okagawa, Tomohiro, Konnai, Satoru, Nishimori, Asami, Maekawa, Naoya, Ikebuchi, Ryoyo, Goto, Shinya, Nakajima, Chie, Kohara, Junko, Ogasawara, Satoshi, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461298/ https://www.ncbi.nlm.nih.gov/pubmed/28638381 http://dx.doi.org/10.3389/fimmu.2017.00650

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