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Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

Genetic variations in the vacuolar protein sorting 10 protein (Vps10p) family have been linked to Alzheimer’s disease (AD). Here we demonstrate deposition of fragments from the Vps10p member sortilin at senile plaques (SPs) in aged and AD human cerebrum. Sortilin changes were characterized in postmo...

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Detalles Bibliográficos
Autores principales:	Hu, Xia, Hu, Zhao-Lan, Li, Zheng, Ruan, Chun-Sheng, Qiu, Wen-Ying, Pan, Aihua, Li, Chang-Qi, Cai, Yan, Shen, Lu, Chu, Yaping, Tang, Bei-Sha, Cai, Huaibin, Zhou, Xin-Fu, Ma, Chao, Yan, Xiao-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461299/ https://www.ncbi.nlm.nih.gov/pubmed/28638323 http://dx.doi.org/10.3389/fnana.2017.00045

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