Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

The presence of latent HIV-1 in infected individuals represents a major barrier preventingviral eradication. For that reason, reactivation of latent viruses in the presence of antiretroviral regimens has been proposed as a therapeutic strategy to achieve remission. We screened for small molecules an...

Descripción completa

Detalles Bibliográficos
Autores principales: Bosque, Alberto, Nilson, Kyle A., Macedo, Amanda B., Spivak, Adam M., Archin, Nancie M., Van Wagoner, Ryan M., Martins, Laura J., Novis, Camille L., Szaniawski, Matthew A., Ireland, Chris M., Margolis, David M., Price, David H., Planelles, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461578/
https://www.ncbi.nlm.nih.gov/pubmed/28147284
http://dx.doi.org/10.1016/j.celrep.2017.01.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461578/
https://www.ncbi.nlm.nih.gov/pubmed/28147284
http://dx.doi.org/10.1016/j.celrep.2017.01.022

Ejemplares similares