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Chronic diazepam administration increases the expression of Lcn2 in the CNS

Benzodiazepines (BZDs), which bind with high affinity to gamma‐aminobutyric acid type A receptors (GABA(A)‐Rs) and potentiate the effects of GABA, are widely prescribed for anxiety, insomnia, epileptic discharge, and as anticonvulsants. The long‐term use of BZDs is limited due to adverse effects suc...

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Detalles Bibliográficos
Autores principales: Furukawa, Tomonori, Shimoyama, Shuji, Miki, Yasuo, Nikaido, Yoshikazu, Koga, Kohei, Nakamura, Kazuhiko, Wakabayashi, Koichi, Ueno, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461642/
https://www.ncbi.nlm.nih.gov/pubmed/28596835
http://dx.doi.org/10.1002/prp2.283

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