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Genome‐wide DNA methylation profiling of CpG islands in a morpholino anthracycline derivative‐resistant leukemia cell line: p38α as a novel candidate for resistance
Effective leukemia treatment is seriously hampered by drug resistance. We previously showed that aberrant methylation of the topoisomerase II α gene causes altered gene expression and acquired drug resistance in etoposide‐resistant leukemia cells. In this study, we analyzed the genome‐wide methylati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461645/ https://www.ncbi.nlm.nih.gov/pubmed/28596837 http://dx.doi.org/10.1002/prp2.285 |