Cargando…
Absorption, distribution, metabolism, and excretion of [(14)C]‐dasotraline in humans
Dasotraline is a dopamine and norepinephrine reuptake inhibitor, and the early clinical trials show a slow absorption and long elimination half‐life. To investigate the absorption, distribution, metabolism, and excretion of dasotraline in humans, a single dose of [(14)C]‐dasotraline was administered...
Autores principales: | Chen, Yu‐Luan, Skende, Estela, Lin, Jing, Yi, Yijun, Wang, Peter L., Wills, Sarah, Wilkinson, H. Scott, Koblan, Kenneth S., Hopkins, Seth C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461651/ https://www.ncbi.nlm.nih.gov/pubmed/28596833 http://dx.doi.org/10.1002/prp2.281 |
Ejemplares similares
-
Pharmacokinetics and Exposure-Response Relationships of Dasotraline in the Treatment of Attention-Deficit/Hyperactivity Disorder in Adults
por: Hopkins, Seth C., et al.
Publicado: (2015) -
The rate of dasotraline brain entry is slow following intravenous administration
por: Lew, Robert, et al.
Publicado: (2020) -
Efficacy and Safety of Dasotraline in Children With ADHD: A Laboratory Classroom Study
por: Wigal, Sharon B., et al.
Publicado: (2019) -
Dasotraline for the Treatment of Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept Trial in Adults
por: Koblan, Kenneth S, et al.
Publicado: (2015) -
Absorption, distribution, metabolism, and excretion of [(14)C]-labeled naloxegol in healthy subjects
por: Bui, Khanh, et al.
Publicado: (2015)