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The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

Rev1 is a deoxycytidyl transferase associated with DNA translesion synthesis (TLS). In addition to its catalytic domain, Rev1 possesses a so-called BRCA1 C-terminal (BRCT) domain. Here, we describe cells and mice containing a targeted deletion of this domain. Rev1(B/B) mice are healthy, fertile and...

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Detalles Bibliográficos
Autores principales:	Jansen, Jacob G., Tsaalbi-Shtylik, Anastasia, Langerak, Petra, Calléja, Fabienne, Meijers, Caro M., Jacobs, Heinz, de Wind, Niels
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546167/ https://www.ncbi.nlm.nih.gov/pubmed/15653636 http://dx.doi.org/10.1093/nar/gki189

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