Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

BACKGROUND: Sarcospan (SSPN) is a transmembrane protein that interacts with the sarcoglycans (SGs) to form a tight subcomplex within the dystrophin-glycoprotein complex that spans the sarcolemma and interacts with laminin in the extracellular matrix. Overexpression of SSPN ameliorates Duchenne muscu...

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Detalles Bibliográficos
Autores principales: Peter, Angela K., Miller, Gaynor, Capote, Joana, DiFranco, Marino, Solares-Pérez, Alhondra, Wang, Emily L., Heighway, Jim, Coral-Vázquez, Ramón M., Vergara, Julio, Crosbie-Watson, Rachelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461684/
https://www.ncbi.nlm.nih.gov/pubmed/28587652
http://dx.doi.org/10.1186/s13395-017-0127-9

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