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KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment

BACKGROUND: Type 2 diabetes (T2D) is a worldwide epidemic with considerable health and economic consequences. Sulfonylureas are widely used drugs for the treatment of patients with T2D. KCNJ11 and ABCC8 encode the K(ir)6.2 (pore-forming subunit) and SUR1 (regulatory subunit that binds to sulfonylure...

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Detalles Bibliográficos
Autores principales:	Song, Jingwen, Yang, Yunzhong, Mauvais-Jarvis, Franck, Wang, Yu-Ping, Niu, Tianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461698/ https://www.ncbi.nlm.nih.gov/pubmed/28587604 http://dx.doi.org/10.1186/s12881-017-0422-7

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