Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study

BACKGROUND: Increasing evidences indicate that an unbalance between tryptases and their endogenous inhibitors, leading to an increased proteolytic activity, is implicated in the pathophysiology of rheumatoid arthritis. The aim of the present study was to evaluate the impact of tryptase inhibition on...

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Detalles Bibliográficos
Autores principales: Denadai-Souza, Alexandre, Ribeiro, Camilla Moreira, Rolland, Corinne, Thouard, Anne, Deraison, Céline, Scavone, Cristoforo, Gonzalez-Dunia, Daniel, Vergnolle, Nathalie, Avellar, Maria Christina Werneck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461776/
https://www.ncbi.nlm.nih.gov/pubmed/28587618
http://dx.doi.org/10.1186/s13075-017-1326-9

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