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Non-cross-linking gold nanoparticle aggregation as a detection method for single-base substitutions
Aggregation of DNA-modified gold nanoparticles in a non-cross-linking configuration has extraordinary selectivity against terminal mismatch of the surface-bound duplex. In this paper, we demonstrate the utility of this selectivity for detection of single-base substitutions. The samples were prepared...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546178/ https://www.ncbi.nlm.nih.gov/pubmed/15640441 http://dx.doi.org/10.1093/nar/gni007 |