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BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes
Bisulfite genomic sequencing is the most widely used technique to analyze the 5-methylation of cytosines, the prevalent covalent DNA modification in mammals. The process is based on the selective transformation of unmethylated cytosines to uridines. Then, the investigated genomic regions are PCR amp...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546182/ https://www.ncbi.nlm.nih.gov/pubmed/15653630 http://dx.doi.org/10.1093/nar/gni012 |