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Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation

BACKGROUND: Studies in rodents and some studies in humans have shown that conjugated linoleic acid (CLA), especially its trans-10, cis-12 isomer, reduces body fat content. However, some but not all studies in mice and humans (though none in rats) have found that CLA promotes insulin resistance. The...

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Detalles Bibliográficos
Autores principales:	Wargent, Ed, Sennitt, Matthew V, Stocker, Claire, Mayes, Andrew E, Brown, Louise, O'Dowd, Jacqueline, Wang, Steven, Einerhand, Alexandra WC, Mohede, Inge, Arch, Jonathan RS, Cawthorne, Michael A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546236/ https://www.ncbi.nlm.nih.gov/pubmed/15642120 http://dx.doi.org/10.1186/1476-511X-4-3

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