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Dichloroacetate affects proliferation but not apoptosis in canine mammary cell lines

Targeting mitochondrial energy metabolism is a novel approach in cancer research and can be traced back to the description of the Warburg effect. Dichloroacetate, a controversially discussed subject of many studies in cancer research, is a pyruvate dehydrogenase kinase inhibitor. Dichloroacetate cau...

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Detalles Bibliográficos
Autores principales:	Harting, Tatjana P., Stubbendorff, Mandy, Hammer, Susanne C., Schadzek, Patrik, Ngezahayo, Anaclet, Murua Escobar, Hugo, Nolte, Ingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462399/ https://www.ncbi.nlm.nih.gov/pubmed/28591165 http://dx.doi.org/10.1371/journal.pone.0178744

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