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Senescent cells: New target for an old treatment?

Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in normal tissues. Senescent cells acquire a pro-inflammatory phenotype which contributes to local and systemic inflammation. Eliminating senescent cells reduce several short- and long-term effects of the dru...

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Detalles Bibliográficos
Autor principal: Demaria, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462517/
https://www.ncbi.nlm.nih.gov/pubmed/28616578
http://dx.doi.org/10.1080/23723556.2017.1299666

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