Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

Insulin, downstream of Akt activation, promotes glucose uptake into fat and muscle cells to lower postprandial blood glucose, an enforced change in cellular metabolism to maintain glucose homeostasis. This effect is mediated by the Glut4 glucose transporter. Growth factors also enhance glucose uptak...

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Detalles Bibliográficos
Autores principales: Beg, Muheeb, Abdullah, Nazish, Thowfeik, Fathima Shazna, Altorki, Nasser K, McGraw, Timothy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462539/
https://www.ncbi.nlm.nih.gov/pubmed/28589878
http://dx.doi.org/10.7554/eLife.26896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462539/
https://www.ncbi.nlm.nih.gov/pubmed/28589878
http://dx.doi.org/10.7554/eLife.26896

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