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Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
Insulin, downstream of Akt activation, promotes glucose uptake into fat and muscle cells to lower postprandial blood glucose, an enforced change in cellular metabolism to maintain glucose homeostasis. This effect is mediated by the Glut4 glucose transporter. Growth factors also enhance glucose uptak...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462539/ https://www.ncbi.nlm.nih.gov/pubmed/28589878 http://dx.doi.org/10.7554/eLife.26896 |