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Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
Severe infections like sepsis lead frequently to cardiomyopathy. The mechanisms are unclear and an optimal therapy for septic cardiomyopathy still lacks. The aim of this study is to establish an endotoxin-induced inflammatory model using human induced pluripotent stem cell (hiPSC) derived cardiomyoc...
Autores principales: | Yücel, Gökhan, Zhao, Zhihan, El-Battrawy, Ibrahim, Lan, Huan, Lang, Siegfried, Li, Xin, Buljubasic, Fanis, Zimmermann, Wolfram-Hubertus, Cyganek, Lukas, Utikal, Jochen, Ravens, Ursula, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiao-Bo, Akin, Ibrahim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462745/ https://www.ncbi.nlm.nih.gov/pubmed/28592841 http://dx.doi.org/10.1038/s41598-017-03147-4 |
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