TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in mice

Hepatocyte death, as well as the following inflammatory and fibrogenic signaling cascades, is the key trigger of liver fibrosis. Here, we isolated hepatocytes from CCl(4)-induced fibrotic liver and found that hepatocyte lincRNA-p21 significantly increased during liver fibrosis. The increase of hepat...

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Detalles Bibliográficos
Autores principales: Tu, Xiaolong, Zhang, Yuanyuan, Zheng, Xiuxiu, Deng, Jia, Li, Huanan, Kang, Zhiqian, Cao, Zhipeng, Huang, Zhen, Ding, Zhi, Dong, Lei, Chen, Jiangning, Zang, Yuhui, Zhang, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462818/
https://www.ncbi.nlm.nih.gov/pubmed/28592847
http://dx.doi.org/10.1038/s41598-017-03175-0

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