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Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy

Cytolethal distending toxin (CDT) produced by Campylobacter jejuni contains three subunits: CdtA, CdtB, and CdtC. Among these three toxin subunits, CdtB is the toxic moiety of CDT with DNase I activity, resulting in DNA double-strand breaks (DSB) and, consequently, cell cycle arrest at the G2/M stag...

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Detalles Bibliográficos
Autores principales:	Lin, Hwai-Jeng, Liu, Hsin-Ho, Lin, Chia-Der, Kao, Min-Chuan, Chen, Yu-An, Chiang-Ni, Chuan, Jiang, Zhi-Pei, Huang, Mei-Zi, Lin, Chun-Jung, Lo, U-Ging, Lin, Li-Chiung, Lai, Cheng-Kuo, Lin, Ho, Hsieh, Jer-Tsong, Chiu, Cheng-Hsun, Lai, Chih-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462984/ https://www.ncbi.nlm.nih.gov/pubmed/28642840 http://dx.doi.org/10.3389/fcimb.2017.00223

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