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Methionine tumor starvation by erythrocyte‐encapsulated methionine gamma‐lyase activity controlled with per os vitamin B6

Erymet is a new therapy resulting from the encapsulation of a methionine gamma‐lyase (MGL; EC number 4.4.1.11) in red blood cells (RBC). The aim of this study was to evaluate erymet potential efficacy in methionine (Met)‐dependent cancers. We produced a highly purified MGL using a cGMP process, dete...

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Detalles Bibliográficos
Autores principales:	Gay, Fabien, Aguera, Karine, Sénéchal, Karine, Tainturier, Angie, Berlier, Willy, Maucort‐Boulch, Delphine, Honnorat, Jérôme, Horand, Françoise, Godfrin, Yann, Bourgeaux, Vanessa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463067/ https://www.ncbi.nlm.nih.gov/pubmed/28544589 http://dx.doi.org/10.1002/cam4.1086

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