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Optimization of liposomal topotecan for use in treating neuroblastoma

The purpose of this work was to develop an optimized liposomal formulation of topotecan for use in the treatment of patients with neuroblastoma. Drug exposure time studies were used to determine that topotecan (Hycamtin) exhibited great cytotoxic activity against SK‐N‐SH, IMR‐32 and LAN‐1 neuroblast...

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Detalles Bibliográficos
Autores principales:	Chernov, Lina, Deyell, Rebecca J., Anantha, Malathi, Dos Santos, Nancy, Gilabert‐Oriol, Roger, Bally, Marcel B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463073/ https://www.ncbi.nlm.nih.gov/pubmed/28544814 http://dx.doi.org/10.1002/cam4.1083

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