High ubiquitin‐specific protease 44 expression induces DNA aneuploidy and provides independent prognostic information in gastric cancer

Chromosomal instability (CIN), characterized by aneuploidy, is a major molecular subtype of gastric cancer. The deubiquitinase USP44 is an important regulator of APC activation in the spindle checkpoint and leads to proper chromosome separation to prevent aneuploidy. Aberrant expression of USP44 lea...

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Detalles Bibliográficos
Autores principales: Nishimura, Sho, Oki, Eiji, Ando, Koji, Iimori, Makoto, Nakaji, Yu, Nakashima, Yuichiro, Saeki, Hiroshi, Oda, Yoshinao, Maehara, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463085/
https://www.ncbi.nlm.nih.gov/pubmed/28544703
http://dx.doi.org/10.1002/cam4.1090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463085/
https://www.ncbi.nlm.nih.gov/pubmed/28544703
http://dx.doi.org/10.1002/cam4.1090

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