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A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging

BACKGROUND: Elderly female patients complaints of acute low back pain (LBP) may involve vertebral fracture (VF), among which occult VF (OVF: early-stage VF without any morphological change) is often missed to be detected by primary X-ray examination. The current study aimed to investigate the preval...

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Autores principales: Terakado, Atsushi, Orita, Sumihisa, Inage, Kazuhide, Kubota, Go, Kanzaki, Tomohiro, Mori, Hiroshi, Shinohara, Yuji, Nakamura, Junichi, Matsuura, Yusuke, Aoki, Yasuchika, Furuya, Takeo, Koda, Masao, Ohtori, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463094/
https://www.ncbi.nlm.nih.gov/pubmed/28630567
http://dx.doi.org/10.1155/2017/9265259
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author Terakado, Atsushi
Orita, Sumihisa
Inage, Kazuhide
Kubota, Go
Kanzaki, Tomohiro
Mori, Hiroshi
Shinohara, Yuji
Nakamura, Junichi
Matsuura, Yusuke
Aoki, Yasuchika
Furuya, Takeo
Koda, Masao
Ohtori, Seiji
author_facet Terakado, Atsushi
Orita, Sumihisa
Inage, Kazuhide
Kubota, Go
Kanzaki, Tomohiro
Mori, Hiroshi
Shinohara, Yuji
Nakamura, Junichi
Matsuura, Yusuke
Aoki, Yasuchika
Furuya, Takeo
Koda, Masao
Ohtori, Seiji
author_sort Terakado, Atsushi
collection PubMed
description BACKGROUND: Elderly female patients complaints of acute low back pain (LBP) may involve vertebral fracture (VF), among which occult VF (OVF: early-stage VF without any morphological change) is often missed to be detected by primary X-ray examination. The current study aimed to investigate the prevalence of VF and OVF and the diagnostic accuracy of the initial X-ray in detecting OVF. METHOD: Subjects were elderly women (>70 years old) complaining of acute LBP with an accurate onset date. Subjects underwent lumbar X-ray, magnetic resonance imaging (MRI), and bone mineral density (BMD) measurement at their first visit. The distribution of radiological findings from X-ray and magnetic resonance imaging (MRI) as well as the calculation of the prevalence of VF and OVF are investigated. RESULTS: The prevalence of VF among elderly women with LBP was 76.5% and L1 was the most commonly injured level. Among VF cases, the prevalence of OVF was 33.3%. Furthermore, osteoporotic patients tend to show increased prevalence of VF (87.5%). The predictive values in detecting VF on the initial plain X-ray were as follows: sensitivity, 51.3%; specificity, 75.0%; and accuracy rate, 56.7%. CONCLUSIONS: Acute LBP patients may suffer vertebral injury with almost no morphologic change in X-ray, which can be detected using MRI.
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spelling pubmed-54630942017-06-19 A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging Terakado, Atsushi Orita, Sumihisa Inage, Kazuhide Kubota, Go Kanzaki, Tomohiro Mori, Hiroshi Shinohara, Yuji Nakamura, Junichi Matsuura, Yusuke Aoki, Yasuchika Furuya, Takeo Koda, Masao Ohtori, Seiji Pain Res Manag Research Article BACKGROUND: Elderly female patients complaints of acute low back pain (LBP) may involve vertebral fracture (VF), among which occult VF (OVF: early-stage VF without any morphological change) is often missed to be detected by primary X-ray examination. The current study aimed to investigate the prevalence of VF and OVF and the diagnostic accuracy of the initial X-ray in detecting OVF. METHOD: Subjects were elderly women (>70 years old) complaining of acute LBP with an accurate onset date. Subjects underwent lumbar X-ray, magnetic resonance imaging (MRI), and bone mineral density (BMD) measurement at their first visit. The distribution of radiological findings from X-ray and magnetic resonance imaging (MRI) as well as the calculation of the prevalence of VF and OVF are investigated. RESULTS: The prevalence of VF among elderly women with LBP was 76.5% and L1 was the most commonly injured level. Among VF cases, the prevalence of OVF was 33.3%. Furthermore, osteoporotic patients tend to show increased prevalence of VF (87.5%). The predictive values in detecting VF on the initial plain X-ray were as follows: sensitivity, 51.3%; specificity, 75.0%; and accuracy rate, 56.7%. CONCLUSIONS: Acute LBP patients may suffer vertebral injury with almost no morphologic change in X-ray, which can be detected using MRI. Hindawi 2017 2017-05-25 /pmc/articles/PMC5463094/ /pubmed/28630567 http://dx.doi.org/10.1155/2017/9265259 Text en Copyright © 2017 Atsushi Terakado et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Terakado, Atsushi
Orita, Sumihisa
Inage, Kazuhide
Kubota, Go
Kanzaki, Tomohiro
Mori, Hiroshi
Shinohara, Yuji
Nakamura, Junichi
Matsuura, Yusuke
Aoki, Yasuchika
Furuya, Takeo
Koda, Masao
Ohtori, Seiji
A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title_full A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title_fullStr A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title_full_unstemmed A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title_short A Clinical Prospective Observational Cohort Study on the Prevalence and Primary Diagnostic Accuracy of Occult Vertebral Fractures in Aged Women with Acute Lower Back Pain Using Magnetic Resonance Imaging
title_sort clinical prospective observational cohort study on the prevalence and primary diagnostic accuracy of occult vertebral fractures in aged women with acute lower back pain using magnetic resonance imaging
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463094/
https://www.ncbi.nlm.nih.gov/pubmed/28630567
http://dx.doi.org/10.1155/2017/9265259
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