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Tightly controlled MRTF-A activity regulates epithelial differentiation during formation of mammary acini
BACKGROUND: Myocardin-related transcription factors (MRTF) A and B link actin dynamics and mechanotransduction to gene expression. In mice, MRTF-A is involved in mammary gland differentiation, but its role in human mammary epithelial cells remains unclear. METHODS: Three-dimensional cultures of huma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463372/ https://www.ncbi.nlm.nih.gov/pubmed/28592291 http://dx.doi.org/10.1186/s13058-017-0860-3 |