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Regulating STING in health and disease

The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INterferon Genes (STING)”. STING has been found to mediate type I interferon response downstrea...

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Detalles Bibliográficos
Autores principales: Li, Yang, Wilson, Heather L., Kiss-Toth, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463399/
https://www.ncbi.nlm.nih.gov/pubmed/28596706
http://dx.doi.org/10.1186/s12950-017-0159-2