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Evaluation of Attenuated Tumor Antigens and the Implications for Peptide-Based Cancer Vaccine Development

INTRODUCTION: Peptide vaccines offer anti-tumor efficacy with very low toxicity. However, repeat stimulation with an immunogenic peptide leads to activation induced cell death (AICD), decreasing efficacy. We engineered variants of an immunogenic peptide (E39) and tested their ability to induce a rob...

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Detalles Bibliográficos
Autores principales:	Berry, JS, Vreeland, TJ, Hale, DF, Jackson, DO, Trappey, AF, Greene, JM, Hardin, MO, Herbert, GS, Clifton, GT, Peoples, GE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463441/ https://www.ncbi.nlm.nih.gov/pubmed/28607601 http://dx.doi.org/10.7150/jca.16450

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