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Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome

BACKGROUND: Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivities in patients with fragile X syndrome (FXS). The current study investigat...

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Detalles Bibliográficos
Autores principales: Ethridge, Lauren E., White, Stormi P., Mosconi, Matthew W., Wang, Jun, Pedapati, Ernest V., Erickson, Craig A., Byerly, Matthew J., Sweeney, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463459/
https://www.ncbi.nlm.nih.gov/pubmed/28596820
http://dx.doi.org/10.1186/s13229-017-0140-1