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Wnt target genes and where to find them

Wnt/β-catenin signaling is highly conserved throughout metazoans, is required for numerous essential events in development, and serves as a stem cell niche signal in many contexts. Misregulation of the pathway is linked to several human pathologies, most notably cancer. Wnt stimulation results in st...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Aravinda-Bharathi, Cadigan, Ken M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464219/
https://www.ncbi.nlm.nih.gov/pubmed/28649368
http://dx.doi.org/10.12688/f1000research.11034.1