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Hepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk

HIV‐infected patients show a markedly increased risk of delayed hypersensitivity (HS) reactions to potentiated sulfonamide antibiotics (trimethoprim/sulfamethoxazole or TMP/SMX). Some studies have suggested altered SMX biotransformation in HIV infection, but hepatic biotransformation pathways have n...

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Detalles Bibliográficos
Autores principales: Wong, Yat Yee, Johnson, Brian, Friedrich, Thomas C., Trepanier, Lauren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464341/
https://www.ncbi.nlm.nih.gov/pubmed/28603631
http://dx.doi.org/10.1002/prp2.312