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Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies
Synucleinopathies are a group of neurodegenerative disorders sharing the common feature of misfolding and accumulation of the presynaptic protein α‐synuclein (α‐syn) into insoluble aggregates. Within this diverse group, Dementia with Lewy Bodies (DLB) is characterized by the aberrant accumulation of...
Autores principales: | Goldberg, Natalie R.S., Marsh, Samuel E., Ochaba, Joseph, Shelley, Brandon C., Davtyan, Hayk, Thompson, Leslie M., Steffan, Joan S., Svendsen, Clive N., Blurton‐Jones, Mathew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464354/ https://www.ncbi.nlm.nih.gov/pubmed/28225193 http://dx.doi.org/10.1002/sctm.16-0362 |
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