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Soft-tissue sarcomas in the head and neck: 25 years of experience
Sarcomas are infrequent and heterogeneous tumours. They represent 1–2% of all malignant neoplasms in adults and between 4% and 10% of head and neck cancers. METHODS: The research was retrospective, descriptive, and cross-sectional. RESULTS: A study population of 62 patients with a mean age of 44 yea...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464559/ https://www.ncbi.nlm.nih.gov/pubmed/28626490 http://dx.doi.org/10.3332/ecancer.2017.740 |
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author | Liuzzi, Juan Francisco Da Cunha, Maribel Salas, Daniuska Siso, Saul Garriga, Esteban |
author_facet | Liuzzi, Juan Francisco Da Cunha, Maribel Salas, Daniuska Siso, Saul Garriga, Esteban |
author_sort | Liuzzi, Juan Francisco |
collection | PubMed |
description | Sarcomas are infrequent and heterogeneous tumours. They represent 1–2% of all malignant neoplasms in adults and between 4% and 10% of head and neck cancers. METHODS: The research was retrospective, descriptive, and cross-sectional. RESULTS: A study population of 62 patients with a mean age of 44 years was obtained; the most frequent location was the soft tissues of the neck (25.3%) and the mean tumour size was 7.1 cm; the most frequent diagnosis was undifferentiated pleomorphic sarcoma (25.5%) and the majority were stage III (41.4%). The lowest survival rates were associated with T2a and T2b tumours (p = 0.014), the presence of lymph node metastasis (p = 0.001), advanced stages (p = 0.003), and invasion of bone, blood vessels and/or nerves (p = 0.008). CONCLUSIONS: Late diagnosis is the main factor associated with decreased survival in patients with head and neck sarcomas. |
format | Online Article Text |
id | pubmed-5464559 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-54645592017-06-16 Soft-tissue sarcomas in the head and neck: 25 years of experience Liuzzi, Juan Francisco Da Cunha, Maribel Salas, Daniuska Siso, Saul Garriga, Esteban Ecancermedicalscience Case Report Sarcomas are infrequent and heterogeneous tumours. They represent 1–2% of all malignant neoplasms in adults and between 4% and 10% of head and neck cancers. METHODS: The research was retrospective, descriptive, and cross-sectional. RESULTS: A study population of 62 patients with a mean age of 44 years was obtained; the most frequent location was the soft tissues of the neck (25.3%) and the mean tumour size was 7.1 cm; the most frequent diagnosis was undifferentiated pleomorphic sarcoma (25.5%) and the majority were stage III (41.4%). The lowest survival rates were associated with T2a and T2b tumours (p = 0.014), the presence of lymph node metastasis (p = 0.001), advanced stages (p = 0.003), and invasion of bone, blood vessels and/or nerves (p = 0.008). CONCLUSIONS: Late diagnosis is the main factor associated with decreased survival in patients with head and neck sarcomas. Cancer Intelligence 2017-06-02 /pmc/articles/PMC5464559/ /pubmed/28626490 http://dx.doi.org/10.3332/ecancer.2017.740 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Liuzzi, Juan Francisco Da Cunha, Maribel Salas, Daniuska Siso, Saul Garriga, Esteban Soft-tissue sarcomas in the head and neck: 25 years of experience |
title | Soft-tissue sarcomas in the head and neck: 25 years of experience |
title_full | Soft-tissue sarcomas in the head and neck: 25 years of experience |
title_fullStr | Soft-tissue sarcomas in the head and neck: 25 years of experience |
title_full_unstemmed | Soft-tissue sarcomas in the head and neck: 25 years of experience |
title_short | Soft-tissue sarcomas in the head and neck: 25 years of experience |
title_sort | soft-tissue sarcomas in the head and neck: 25 years of experience |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464559/ https://www.ncbi.nlm.nih.gov/pubmed/28626490 http://dx.doi.org/10.3332/ecancer.2017.740 |
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