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High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats

BACKGROUND: High dietary sodium aggravates renal disease by affecting blood pressure and by its recently shown pro-inflammatory and pro-fibrotic effects. Moreover, pro-inflammatory modification of renal heparan sulfate (HS) can induce tissue remodeling. We aim to investigate if high sodium intake in...

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Detalles Bibliográficos
Autores principales: Hijmans, Ryanne S., Shrestha, Pragyi, Sarpong, Kwaku A., Yazdani, Saleh, el Masri, Rana, de Jong, Wilhelmina H. A., Navis, Gerjan, Vivès, Romain R., van den Born, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464595/
https://www.ncbi.nlm.nih.gov/pubmed/28594849
http://dx.doi.org/10.1371/journal.pone.0178940