Cargando…

Oral uricase eliminates blood uric acid in the hyperuricemic pig model

An elevated level of serum uric acid—hyperuricemia, is strongly associated with the development of gout and chronic kidney disease (CKD) which is often accompanied by a significantly reduced glomerular filtration rate (GFR). In the present study, we investigated the extra-renal elimination of uric a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szczurek, Paulina, Mosiichuk, Nadia, Woliński, Jarosław, Yatsenko, Tetiana, Grujic, Danica, Lozinska, Liudmyla, Pieszka, Marek, Święch, Ewa, Pierzynowski, Stefan Grzegorz, Goncharova, Kateryna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464639/ https://www.ncbi.nlm.nih.gov/pubmed/28594873 http://dx.doi.org/10.1371/journal.pone.0179195

Ejemplares similares

Oral Treatment With an Engineered Uricase, ALLN-346, Reduces Hyperuricemia, and Uricosuria in Urate Oxidase-Deficient Mice
por: Pierzynowska, Kateryna, et al.
Publicado: (2020)

The inverse relationship between blood amylase and insulin levels in pigs during development, bariatric surgery, and intravenous infusion of amylase
por: Pierzynowska, Kateryna Goncharova, et al.
Publicado: (2018)

Importance of neonatal immunoglobulin transfer for hippocampal development and behaviour in the newborn pig
por: Goncharova, Kateryna, et al.
Publicado: (2017)

Difference in Performance of EPI Pigs Fed Either Lipase-Predigested or Creon®-Supplemented Semielemental Diet
por: Pierzynowski, Stefan G., et al.
Publicado: (2021)

Experiments suggesting extra-digestive effects of enteral pancreatic amylase and its peptides on glucose homeostasis in a pig model
por: Pierzynowski, Stefan G., et al.
Publicado: (2017)

Glucose homeostasis dependency on acini–islet–acinar (AIA) axis communication: a new possible pathophysiological hypothesis regarding diabetes mellitus
por: Pierzynowski, Stefan G., et al.
Publicado: (2018)

Immobilized uricase for automated assay of uric acid in serum
por: León, Luis P., et al.
Publicado: (1982)

The Role of Uric Acid in Human Health: Insights from the Uricase Gene
por: Roman, Youssef M.
Publicado: (2023)

Milk Formula Enriched with Sodium Butyrate Influences Small Intestine Contractility in Neonatal Pigs
por: Słupecka-Ziemilska, Monika, et al.
Publicado: (2022)

Maternal Immunoglobulins in Infants—Are They More Than Just a Form of Passive Immunity?
por: Pierzynowska, Kateryna, et al.
Publicado: (2020)

Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice
por: Meng, Xiaolu, et al.
Publicado: (2017)

Phylogenetic Articulation of Uric Acid Evolution in Mammals and How It Informs a Therapeutic Uricase
por: Li, Ze, et al.
Publicado: (2021)

Pre-digestion of the lipids in infant formula affects gut maturation of the preterm pig
por: Zaworski, Kamil, et al.
Publicado: (2022)

Anti-Incretin Gut Features Induced by Feed Supplementation with Alpha-Amylase: Studies on EPI Pigs
por: Pierzynowska, Kateryna, et al.
Publicado: (2023)

A Potentiometric Indirect Uric Acid Sensor Based on ZnO Nanoflakes and Immobilized Uricase
por: Usman Ali, Syed M., et al.
Publicado: (2012)

An Amperometric Biosensor for Uric Acid Determination Prepared From Uricase Immobilized in Polyaniline-Polypyrrole Film
por: Arslan, Fatma
Publicado: (2008)

Electrochemical detection of uric acid in undiluted human saliva using uricase paper integrated electrodes
por: Han, Seong Hyun, et al.
Publicado: (2022)

Absorption of Polyunsaturated Fatty Acid (PUFA) Is Related to IgG Blood Levels of Neonatal Pigs during the First 48 Hours Postpartum
por: Pierzynowska, Kateryna, et al.
Publicado: (2020)

The Membrane Interactions of Nano-Silica and Its Potential Application in Animal Nutrition
por: Pieszka, Marek, et al.
Publicado: (2019)

Effect and Mechanism of ShiZhiFang on Uric Acid Metabolism in Hyperuricemic Rats
por: Wu, Yansheng, et al.
Publicado: (2018)

Conductimetric Biosensor for the Detection of Uric Acid by Immobilization Uricase on Nata de Coco Membrane—Pt Electrode
por: Mulyasuryani, Ani, et al.
Publicado: (2011)

Aboriginal Bacterial Flora in the Uricase-Deficient Rat Gut is Not the Main Factor Affecting Serum Uric Acid
por: Fan, Nan, et al.
Publicado: (2021)

Uricase Crowding via Polyelectrolyte Layers Coacervation for Carbon Fiber-Based Electrochemical Detection of Uric Acid
por: Baldina, Anna A., et al.
Publicado: (2022)

Uric acid relationships with lipid profile and adiposity indices: Impact of different hyperuricemic thresholds
por: Maloberti, Alessandro, et al.
Publicado: (2022)

Two-point kinetic determination of uric acid in serum with uricase, catalase and aldehyde dehydrogenase on the KONE CD analyser
por: Harff, G. A., et al.
Publicado: (1982)

Uricase-deficient rats with similarly stable serum uric acid to human’s are sensitive model animals for studying hyperuricemia
por: Gao, Yinfang, et al.
Publicado: (2022)

Designed Mini Protein 20 Mimicking Uricase Encapsulated in ZIF-8 as Nanozyme Biosensor for Uric Acid Detection
por: Abdul Aziz, Siti Fatimah Nur, et al.
Publicado: (2022)

Impact of Large Aggregated Uricases and PEG Diol on Accelerated Blood Clearance of PEGylated Canine Uricase
por: Zhang, Chun, et al.
Publicado: (2012)

Determining the Effect of Pancreatic-like Enzymes (PLEMs) Added to the Feed of Pregnant Sows on Fetal Size of Piglets to Minimize IUGR Syndrome Caused by Fetal Malnutrition
por: Pieszka, Marek, et al.
Publicado: (2023)

Comparative effects of green and black tea extracts on lowering serum uric acid in hyperuricemic mice
por: Zhu, Chuang, et al.
Publicado: (2017)

Inhibitory Effects of Apium graveolens on Xanthine Oxidase Activity and Serum Uric Acid Levels in Hyperuricemic Mice
por: Dolati, Karim, et al.
Publicado: (2018)

Lifeceramics-treated water reduces serum uric acid levels and improves hemorheological activity in hyperuricemic rats
por: Li, Kuihua, et al.
Publicado: (2020)

Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion
por: Li, Xuechen, et al.
Publicado: (2020)

Ameliorative Effect of Mannuronate Oligosaccharides on Hyperuricemic Mice via Promoting Uric Acid Excretion and Modulating Gut Microbiota
por: Wei, Biqian, et al.
Publicado: (2023)

Anti-Hyperuricemic and Uricosuric Potential of Berberis vulgaris in Oxonate-Induced Hyperuricemic Rats
por: Bilal, Muhammad, et al.
Publicado: (2021)

Enhancing the Response Rate to Recombinant Uricases in Patients with Gout
por: Schlesinger, Naomi, et al.
Publicado: (2022)

Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice
por: Xu, Lieqiang, et al.
Publicado: (2021)

A highly sensitive uric acid electrochemical biosensor based on a nano-cube cuprous oxide/ferrocene/uricase modified glassy carbon electrode
por: Yan, Qinghua, et al.
Publicado: (2020)

Hyperuricemic PRP in Tendon Cells
por: Andia, I., et al.
Publicado: (2014)

Serum Uric Acid Could Differentiate Acute Myocardial Infarction and Unstable Angina Pectoris in Hyperuricemic Acute Coronary Syndrome Patients
por: Hasic, Sabaheta, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vk34kgi2pqj2q74laon6kj7p9d