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Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation
Box C/D snoRNAs are known to guide site-specific ribose methylation of ribosomal RNA. Here, we demonstrate a novel and unexpected role for box C/D snoRNAs in guiding 18S rRNA acetylation in yeast. Our results demonstrate, for the first time, that the acetylation of two cytosine residues in 18S rRNA...
Autores principales: | Sharma, Sunny, Yang, Jun, van Nues, Rob, Watzinger, Peter, Kötter, Peter, Lafontaine, Denis L. J., Granneman, Sander, Entian, Karl-Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464676/ https://www.ncbi.nlm.nih.gov/pubmed/28542199 http://dx.doi.org/10.1371/journal.pgen.1006804 |
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