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Protection studies of new bis quaternary 2-(hydroxyimino)-N-(pyridin-3yl) acetamide derivatives (HNK-series) oximes against acute poisoning by dichlorvos (DDVP) in Swiss albino mice

The available antidotal therapy against acute poisoning by organophosphates involves the use of atropine alone or in combination with one of the oximes, e.g. 2-PAM, Obidoxime, TMB-4 or HI-6. Each of these oximes has some limitation, raising the question of the universal antidotal efficacy against po...

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Detalles Bibliográficos
Autores principales: Kumar, Pravin, Swami, Devyani, Karade, Hitendra N., Singh, Manindar, Tiwari, Anupma, Singh, Kshetra Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464681/
https://www.ncbi.nlm.nih.gov/pubmed/28652853
http://dx.doi.org/10.1515/intox-2016-0013