BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells

BRCA1 deficiency may perturb the differentiation hierarchy present in the normal mammary gland and is associated with the genesis of breast cancers that are genomically unstable and typically display a basal-like transcriptome. Oriented cell division is a mechanism known to regulate cell fates and t...

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Detalles Bibliográficos
Autores principales: He, Zhengcheng, Kannan, Nagarajan, Nemirovsky, Oksana, Chen, Helen, Connell, Marisa, Taylor, Brian, Jiang, Jihong, Pilarski, Linda M., Fleisch, Markus C., Niederacher, Dieter, Pujana, Miguel Angel, Eaves, Connie J., Maxwell, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464802/
https://www.ncbi.nlm.nih.gov/pubmed/28427147
http://dx.doi.org/10.18632/oncotarget.15688

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