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Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation

BACKGROUND: The epidermal growth factor receptor (EGFR) is an important regulator of cell growth and survival, and is highly variable in tumor cells. The most prevalent variation of the EGFR extracellular domain is the EGFR variant III (EGFRvIII). Some studies imply that EGFRvIII may be responsible...

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Detalles Bibliográficos
Autores principales:	Koch, Dominik Thomas, Pickhard, Anja, Gebel, Lena, Buchberger, Anna Maria S., Bas, Murat, Mogler, Carolin, Reiter, Rudolf, Piontek, Guido, Wirth, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464818/ https://www.ncbi.nlm.nih.gov/pubmed/28427242 http://dx.doi.org/10.18632/oncotarget.15949

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