USP22 drives colorectal cancer invasion and metastasis via epithelial-mesenchymal transition by activating AP4

Ubiquitin specific peptidase 22 (USP22), a putative cancer stem cell marker, is overexpressed in liver metastases of colorectal cancer (CRC). However, the mechanism by which USP22 promotes CRC metastasis remains largely unknown. Here, we report that USP22 and AP4 are simultaneously overexpressed dur...

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Detalles Bibliográficos
Autores principales: Li, Yongmin, Yang, Yanmei, Li, Jingwen, Liu, He, Chen, Fuxun, Li, Bingyang, Cui, Binbin, Liu, Yanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464819/
https://www.ncbi.nlm.nih.gov/pubmed/28427243
http://dx.doi.org/10.18632/oncotarget.15950

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