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Tumor-derived IL-18 induces PD-1 expression on immunosuppressive NK cells in triple-negative breast cancer

PURPOSE: While the inflammatory cytokine interleukin-18 (IL-18) is known to activate natural killer (NK) cells, its precise role in cancer is controversial. In this study, we investigated the role of tumor-derived IL-18 on peripheral blood NK cells in breast cancer patients. RESULTS: In breast cance...

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Detalles Bibliográficos
Autores principales:	Park, In Hae, Yang, Han Na, Lee, Kyoung Joo, Kim, Tae-Sik, Lee, Eun Sook, Jung, So-Youn, Kwon, Youngmee, Kong, Sun-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464822/ https://www.ncbi.nlm.nih.gov/pubmed/28415798 http://dx.doi.org/10.18632/oncotarget.16281

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