Glucose availability controls ATF4-mediated MITF suppression to drive melanoma cell growth

It is well know that cancer cells have adopted an altered metabolism and that glucose is a major source of energy for these cells. In melanoma, enhanced glucose usage is favoured through the hyper-activated MAPK pathway, which suppresses OXPHOS and stimulates glycolysis. However, it has not been add...

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Detalles Bibliográficos
Autores principales: Ferguson, Jennifer, Smith, Michael, Zudaire, Isabel, Wellbrock, Claudia, Arozarena, Imanol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464841/
https://www.ncbi.nlm.nih.gov/pubmed/28380427
http://dx.doi.org/10.18632/oncotarget.16514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464841/
https://www.ncbi.nlm.nih.gov/pubmed/28380427
http://dx.doi.org/10.18632/oncotarget.16514

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