iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancer

Aerobic glycolysis is essential for tumor growth and survival. Activation of multiple carcinogenic signals contributes to metabolism reprogramming during malignant transformation of cancer. Recently nitric oxide has been noted to promote glycolysis but the mechanism remains elusive. We report here t...

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Detalles Bibliográficos
Autores principales: Li, Linlin, Zhu, Lingqun, Hao, Bingtao, Gao, Wenwen, Wang, Qianli, Li, Keyi, Wang, Meng, Huang, Mengqiu, Liu, Zhengjun, Yang, Qiaohong, Li, Xiqing, Zhong, Zhuo, Huang, Wenhua, Xiao, Guanghui, Xu, Yang, Yao, Kaitai, Liu, Qiuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464849/
https://www.ncbi.nlm.nih.gov/pubmed/28380434
http://dx.doi.org/10.18632/oncotarget.16523

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