Cargando…

Correlated high expression of FXR and Sp1 in cancer cells confers a poor prognosis for pancreatic cancer: A study based on TCGA and tissue microarray

Bile acids (BAs) was critical in the initiation and progression of various tumors. However, their prognostic significance in pancreatic cancer was still illusive. In the present study, the expression and biological significance of FXR, a major receptor of BAs, in the lethal disease were evaluated in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Hai, Wu, Lei-Lei, Han, Ting, Zhuo, Meng, Lei, Wang, Cui, Jiu-Jie, Jiao, Feng, Wang, Li-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464866/ https://www.ncbi.nlm.nih.gov/pubmed/28402278 http://dx.doi.org/10.18632/oncotarget.16633

Ejemplares similares

Sp1 and COX2 expression is positively correlated with a poor prognosis in pancreatic ductal adenocarcinoma
por: Hang, Junjie, et al.
Publicado: (2016)

Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer
por: Jiao, Feng, et al.
Publicado: (2016)

High Vimentin Expression Predicts a Poor Prognosis and Progression in Colorectal Cancer: A Study with Meta-Analysis and TCGA Database
por: Du, Le, et al.
Publicado: (2018)

Identification of Prognosis-Related Genes in Bladder Cancer Microenvironment across TCGA Database
por: Zhao, Xin, et al.
Publicado: (2020)

Simultaneous high expression of PLD1 and Sp1 predicts a poor prognosis for pancreatic ductal adenocarcinoma patients
por: Hu, Jiong, et al.
Publicado: (2016)

High WFDC3 gene expression is associated with poor prognosis and reduced immune cells infiltration in pancreatic adenocarcinoma: A study using the TCGA database and bioinformatics analysis
por: Wu, Wei, et al.
Publicado: (2023)

Overexpression of OAS1 Is Correlated With Poor Prognosis in Pancreatic Cancer
por: Lu, Lingling, et al.
Publicado: (2022)

Elevated COX-2 Expression Promotes Angiogenesis Through EGFR/p38-MAPK/Sp1-Dependent Signalling in Pancreatic Cancer
por: Hu, Hai, et al.
Publicado: (2017)

A functional methylation signature to predict the prognosis of Chinese lung adenocarcinoma based on TCGA
por: Wang, Ke, et al.
Publicado: (2021)

Increased expression of Cyclin F in liver cancer predicts poor prognosis: A study based on TCGA database
por: Zelong, Yang, et al.
Publicado: (2021)

Using the TCGA Database to Predict and Analyze Tumor Microenvironment Genes Related to Poor Prognosis of Colon Cancer
por: Chen, Sihan, et al.
Publicado: (2020)

Elevated heparanase expression is associated with poor prognosis in breast cancer: a study based on systematic review and TCGA data
por: Sun, Xu, et al.
Publicado: (2017)

Impact of Global Fxr Deficiency on Experimental Acute Pancreatitis and Genetic Variation in the FXR Locus in Human Acute Pancreatitis
por: Nijmeijer, Rian M., et al.
Publicado: (2014)

Nanog Predicts Poor Prognosis in Human Pancreatic Cancer and Is Downregulated by QingyihuaJi Formula in Pancreatic Cancer Stem Cells
por: Gao, Song, et al.
Publicado: (2016)

CILP2 overexpression correlates with tumor progression and poor prognosis in patients with colorectal cancer in The Cancer Genome Atlas (TCGA) study
por: Huang, Feng, et al.
Publicado: (2020)

FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion
por: Fan, Yichao, et al.
Publicado: (2017)

Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients
por: Chen, Luguang, et al.
Publicado: (2017)

The influence of lncRNAs on the prognosis of prostate cancer based on TCGA database
por: Huang, Hang, et al.
Publicado: (2021)

High Expression of Cancer-Derived Glycosylated Immunoglobulin G Predicts Poor Prognosis in Pancreatic Ductal Adenocarcinoma
por: Cui, Ming, et al.
Publicado: (2020)

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis
por: Gore, Jesse, et al.
Publicado: (2015)

Decreased expression of TNFRSF12A in thyroid gland cancer predicts poor prognosis: A study based on TCGA data
por: Wu, Zeng-Hong, et al.
Publicado: (2020)

High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer
por: Yang, Caiting, et al.
Publicado: (2016)

SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR
por: Cui, Shuang, et al.
Publicado: (2023)

A Five-microRNA Signature for Survival Prognosis in Pancreatic Adenocarcinoma based on TCGA Data
por: Shi, Xiu-Hui, et al.
Publicado: (2018)

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis
por: Xu, Jianwei, et al.
Publicado: (2014)

High Expression of MUC15 Is Correlated with Poor Prognosis of Pancreatic Cancer and Promotes Migration, Invasion, and Chemo-Resistance In Vitro
por: Wang, Shunda, et al.
Publicado: (2020)

miR-888 functions as an oncogene and predicts poor prognosis in colorectal cancer
por: Gao, Su-Jun, et al.
Publicado: (2018)

High Expression of Cancer-Derived Glycosylated Immunoglobulin G Predicts Poor Prognosis in Pancreatic Ductal Adenocarcinoma: Erratum
por: Cui, Ming, et al.
Publicado: (2021)

Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation
por: Xu, Pan-ling, et al.
Publicado: (2023)

Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data
por: Zeng, Zhili, et al.
Publicado: (2020)

Elevated expression of mitochondrial transcription elongation factor (TEFM) predicts poor prognosis in low grade glioma—an analysis of the Cancer Genome Atlas (TCGA) dataset
por: Li, Sufen, et al.
Publicado: (2020)

Identification of Upregulated HNRNPs Associated with Poor Prognosis in Pancreatic Cancer
por: Qiao, Lu, et al.
Publicado: (2019)

Prognostic Biomarkers in Pancreatic Cancer: Avoiding Errata When Using the TCGA Dataset
por: Nicolle, Remy, et al.
Publicado: (2019)

Natural Product 2-Oxokolavenol Is a Novel FXR Agonist
por: Guo, Fusheng, et al.
Publicado: (2022)

Early Diagnosis to Improve the Poor Prognosis of Pancreatic Cancer
por: Kikuyama, Masataka, et al.
Publicado: (2018)

Long non-coding RNA LINC02613 is a prognostic biomarker for breast cancer and correlates with the cell cycle and immune infiltration based on TCGA data
por: Cui, Mengyao, et al.
Publicado: (2022)

Overexpression of ICAM-1 Predicts Poor Survival in High-Grade Serous Ovarian Carcinoma: A Study Based on TCGA and GEO Databases and Tissue Microarray
por: Wang, Shasha, et al.
Publicado: (2019)

An Integrated Microarray Analysis Reveals Significant Diagnostic and Prognostic Biomarkers in Pancreatic Cancer
por: Yang, Zhi-Qiang, et al.
Publicado: (2020)

Increased MPO in Colorectal Cancer Is Associated With High Peripheral Neutrophil Counts and a Poor Prognosis: A TCGA With Propensity Score-Matched Analysis
por: Weng, Meilin, et al.
Publicado: (2022)

Increased Expression of KNSTRN in Lung Adenocarcinoma Predicts Poor Prognosis: A Bioinformatics Analysis Based on TCGA Data
por: Deng, Pengbo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_viel77l81v6k8qbn12c2murlmn