The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

EGFR pathway is upregulated in malignant gliomas, and its downstream signaling is important for self-renewal of glioma cancer stem-like cells (GSC). p38 mitogen-activated protein kinase (MAPK) signaling, a stress-activated signaling cascade with suppressive and permissive effects on tumorigenesis, c...

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Detalles Bibliográficos
Autores principales: Soeda, Akio, Lathia, Justin, Williams, Brian J., Wu, Qiulian, Gallagher, Joseph, Androutsellis-Theotokis, Andreas, Giles, Amber J., Yang, Chunzhang, Zhuang, Zhengping, Gilbert, Mark R., Rich, Jeremy N., Park, Deric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464870/
https://www.ncbi.nlm.nih.gov/pubmed/28410196
http://dx.doi.org/10.18632/oncotarget.16741

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