Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling

To date, hypoxia-inducible factor 1a (HIF-1a) and astrocyte elevated gene-1 (AEG-1) have been involved in the proliferation, migration and morphological changes of vascular smooth muscle cells. However, the potential relationship of HIF-1a-AEG-1 pathway in human aortic smooth muscle cell (HASMC) has...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Fang, Changcun, Shen, Yuwen, Liu, Zhengqin, Zhang, Min, Ma, Bingbing, Pang, Xinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464872/
https://www.ncbi.nlm.nih.gov/pubmed/28415624
http://dx.doi.org/10.18632/oncotarget.16448

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