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Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling

Here we report the identification and characterization of a novel high molecular weight isoform of tropomyosin, Tpm4.1, expressed from the human TPM4 gene. Tpm4.1 expression is down-regulated in a subset of breast cancer cells compared with untransformed MCF10A breast epithelial cells and in highly...

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Detalles Bibliográficos
Autores principales:	Jeong, SukYeong, Lim, SunYoung, Schevzov, Galina, Gunning, Peter W., Helfman, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464889/ https://www.ncbi.nlm.nih.gov/pubmed/28431393 http://dx.doi.org/10.18632/oncotarget.16825

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