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Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion

BACKGROUND: As one of the most common cancers in men, the pathogenesis of prostate cancer has been widely researched. Aberrant activation of the erb-b2 receptor tyrosine kinase 2 (ERBB2) has been found to play a critical role in metastatic prostate cancer. In our previous study, we demonstrated that...

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Detalles Bibliográficos
Autores principales: Xin, Xianxiang, Gu, Yinmin, Chen, Yang, Huang, Yuanjie, Mo, Zengnan, Hu, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464908/
https://www.ncbi.nlm.nih.gov/pubmed/28422721
http://dx.doi.org/10.18632/oncotarget.16807